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Cowboys vs. Giants odds, line, spread: 2022 Thanksgiving Day NFL picks, predictions by model on 155-109 run

Second place in the NFC East standings is up for grabs when the Dallas Cowboys host the New York Giants as part of the 2022 NFL Thanksgiving Day schedule. The rivals will enter the Thanksgiving NFL 2022 game with identical 7-3 records, although Dallas posted a 23-16 victory at New York in Week 3.

The Cowboys bounced back from a deflating overtime loss at Green Bay with a convincing 40-3 triumph at Minnesota last week, ending the Vikings’ seven-game winning streak. Meanwhile, the Giants are coming off their second defeat in three contests, a 31-18 home setback against Detroit. Dallas rolled to a 30-3 victory in its only previous Thanksgiving meeting with New York in 1992.

Kickoff from AT&T Stadium is set for 4:30 p.m. ET. Dallas is a 10-point favorite in the latest Cowboys vs. Giants odds from Caesars Sportsbook, while the over/under for total points scored is 45.5. Before making any Giants vs. Cowboys picks, you need to see the NFL predictions and betting advice from SportsLine’s Advanced Computer Model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 12 of the 2022 NFL season on an incredible 155-109 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Cowboys vs. Giants and just locked in its picks and Thanksgiving Day NFL predictions. You can head to SportsLine now to see the model’s picks. Here are several NFL odds and betting lines for Giants vs. Cowboys:

  • Cowboys vs. Giants spread: Dallas -10
  • Cowboys vs. Giants over/under: 45.5 points
  • Cowboys vs. Giants money line: Dallas -455, New York +345
  • DAL: Cowboys are 22-8 against the spread in their last 30 games against division-rivals
  • NYG: Giants are 2-9 ATS in their last 11 meetings with Dallas

Why the Cowboys can cover

After losing his first two career starts against New York, Dak Prescott has been outstanding in the series. The 29-year-old quarterback has led Dallas to victory in his last nine outings versus the division-rival, throwing 20 touchdown passes and only three interceptions during the streak. Prescott is looking to become the first signal-caller to win 10 straight starts against the Giants since Roger Staubach reeled off 11 consecutive victories from 1974-79.

The Cowboys lead the NFL with 42 sacks and linebacker Micah Parsons has notched 10 to rank third in the league. Dallas registered five sacks in its first meeting with New York this season, with DeMarcus Lawrence, who has recorded one in each of his last three contests, posting three. The Cowboys’ defense also is first in the NFL against the pass, allowing an average of 174.5 yards, and has permitted a league-low 16.7 points per game. See which team to pick here.

Why the Giants can cover

Daniel Jones is coming off one of the most productive passing performances of his career, as he threw for 341 yards in last Sunday’s 31-18 loss to Detroit. It was the seventh 300-yard outing of the 25-year-old’s career and first since Week 4 of last season, when he set a career-high with 402 yards at New Orleans. Jones also ran for 50 yards against the Lions and gained 79 on the ground in the first meeting with the Cowboys this year.

Saquon Barkley led the Giants with 81 rushing yards in the Week 3 loss to Dallas and scored the team’s lone touchdown.

The 25-year-old was held to a season-low 22 yards on 15 carries last week, but is second in the NFL with 953 and leads the league with 1,163 scrimmage yards. Barkley has registered at least 105 scrimmage yards in three of his four road games this season and posted two of his four 100-yard rushing performances away from home. See which team to pick here.

How to make Cowboys vs. Giants picks

SportsLine’s model is leaning Over on the point total, calling for 46 combined points. The model also says one side of the spread has all the value. You can only see the model’s NFL picks at SportsLine.

New York Giants at Dallas Cowboys: Inactives & Lineup Changes

The New York Giants had no trouble figuring out their Week 12 inactive list. But that’s not necessarily a good thing, as the inactive list consists of injured players who didn’t make the trip to Dallas.

Here is the Giants’ inactive list and what the team is anticipated to be doing to replace their respective presences in the lineup.

TE Daniel Bellinger (eye): Bellinger has been out of action since getting poked in the eye during a Week 7 win over Jacksonville, an injury that resulted in a broken orbital bone and septum. He has made progress in his recovery and is waiting for the last of the double vision he suffered to subside. The Giants signed tight end Lawrence Cager to their roster after using all three standard practice squad elevations on him. Cager took the roster spot that opened when the team placed receiver Wan’Dale Robinson (ACL) on the injured reserve list.

OG Joshua Ezeudu (neck): Ezeudu has been dealing with a neck injury for two weeks. Last week he was removed from the starting lineup in favor of Shane Lemieux, who had been activated off injured reserve that previous week. It’s unclear why Ezeudu didn’t get the start against the Lions, but the rookie was re-inserted into the lineup when Lemieux struggled. Doing so apparently didn’t help Ezeudu’s neck, as he was listed as a non-participant in practice all week and didn’t make the trip with the team.

OG Shane Lemieux (toe): Lemieux’s return from injured reserve didn’t go as expected. In addition to being benched, he aggravated his turf toe, the same injury that landed him on injured reserve at the start of the season. Lemieux was replaced after one half by Ezeudu, but with the rookie also inactive for this week and with Ben Bredeson still on injured reserve (knee), the expectation is that Jack Anderson will step in at left guard.

C Jon Feliciano (neck): Feliciano has reportedly been banged up for the better part of the season but has tried to gut things out. Unfortunately for him, this particular injury is one he couldn’t gut out. Nick Gates, who has looked solid in his return from a severely fractured broken leg, relieved Feliciano last week when he couldn’t go on any longer. Gates will get the start at center, the position he previously held before his gruesome-looking leg injury suffered early in the 2021 season.

CB Adoree’ Jackson (knee): Jackson was injured on a punt return–make that an ill-advised punt return. Head coach Brian Daboll defended the decision to deploy Jackson in that role, saying it was best for the team. However, it turned out to be an unnecessary risk given the lack of depth at the position, which was further exposed with the injury to Fabian Moreau (more on that in the next section). With Jackson sidelined for at least four weeks, the Giants will likely plug Nick Mccloud into the lineup.

Sources: 1,2,3,4,5,6,7

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